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Review Article | Volume 21 (II) Issue:2 (June-Dec, 2022) | Pages 50 - 69
Addressing Antimicrobial Resistance: Strategies, Innovations, System Integration, Challenges and Future Directions
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1
General Directorate of Health Affairs Jazan, Al Rawdah, Jazan-82723, Saudi Arabia
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Riyadh Second Health Cluster, Post Box-3881, Riyadh-13255 - 6729, Saudi Arabia
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Primary Health Care Center, Alasamilh, As Suways, Jazan 82617, Saudi Arabia
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Ahad Rafidah General Hospital, Alwurud, Ahad Rafidah 62242, Saudi Arabia
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Primary Health Care Center- Madhya, Jizan 82714, Saudi Arabia
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Madinah Health Cluster, Saeed bin Alaas Street, Madinah-42351, Saudi Arabia
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Eastern Health Cluster, Othman Ibn Affan Street, Al Muraikabat, Dammam 32253, Kingdom of Saudi Arabia
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Al-Ahsa Health Cluster, Ministry of Health, Rashdiah Street, PO. Box 12944, Al-Ahsa- 31982, Kingdom of Saudi Arabia
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Directorate of Health Affairs Taif, 7238, Qurwa, Taif 26521, Kingdom of Saudi Arabia
Under a Creative Commons license
Open Access
Abstract

With the World Health Organization (WHO) identifying AMR as a pivotal concern, collaborative efforts among healthcare
stakeholders are imperative to mitigate its multifaceted drivers. Pharmacists, occupying a central position within the
healthcare framework, play a pivotal role in antimicrobial stewardship programs (ASPs), ensuring the judicious use of
antimicrobial drugs. Through proactive audits, medication reviews, and adherence to evidence-based guidelines,
pharmacists contribute significantly to curbing the rise and spread of antimicrobial resistance. Moreover, they serve as
educators, imparting crucial insights to patients on the prudent utilization of antibiotics and the importance of treatment
adherence. By emphasizing the perils of antibiotic resistance and advocating for responsible antibiotic usage, pharmacists
contribute to reducing unnecessary antibiotic consumption and mitigating the emergence of resistant strains. In addition
to their roles in antimicrobial stewardship and patient education, pharmacists actively engage in infection prevention and
control measures within healthcare settings. Collaborating closely with infection control teams, pharmacists promote
rigorous hand hygiene practices, advocate for adherence to infection control guidelines, and monitor antimicrobial
utilization patterns to identify areas for improvement. Furthermore, pharmacists play a pivotal role in advocating for
policies and initiatives targeting AMR across various levels, including local, national, and international spheres. Their
involvement in public health campaigns, legislative actions, and research endeavors underscores their commitment to
mitigating AMR and safeguarding the efficacy of antimicrobial agents. Technological innovations further empower
pharmacists in their efforts to combat AMR. From electronic health records (EHR) to artificial intelligence (AI) and
machine learning (ML) algorithms, pharmacists leverage cutting-edge technologies to monitor antimicrobial consumption
accurately, enhance adherence to clinical guidelines, and streamline communication across healthcare teams. Despite
facing challenges such as limited authority and resource constraints, pharmacists' contributions in mitigating AMR remain
indispensable. By strengthening policy frameworks, fostering interdisciplinary collaboration, and leveraging
technological innovations, pharmacists can continue to lead efforts in combatting AMR and preserving the efficacy of
antimicrobial agents for future generations.
 

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